Big Louie


a generic phrase to describe any s-xually transmitted disease, or as a shorthand to describe having multiple stds. some dispute exists as to the proper spelling, but either “big louie” or “big louis” is acceptable.
dude, if a chick ever makes you get tested for the big louie, make sure to p-ss in the cup instead of letting them stick that huge q-tip in there, that sh-t hurts.

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