excessive excretion of homogentisic acid in the urine, caused by a hereditary abnormality of the metabolism of tyrosine and phenylalanine.

alkaptonuria al·kap·to·nu·ri·a or al·cap·to·nu·ri·a (āl-kāp’tə-nur’ē-ə, -nyur’-)
An inherited disorder that affects phenylalanine and tyrosine metabolism and leads to the excretion of homogentisic acid in the urine. Also called homogentisuria.


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