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Immunology. any substance that can stimulate the production of and combine specifically with them.
Pharmacology. any commercial substance that, when injected or absorbed into animal tissues, stimulates the production of .
antigens of a particular type collectively.
Contemporary Examples

At the time his PSA screening revealed only a slightly higher level of the antigen than the cut-off for his age group.
Are PSA Screenings for Prostate Cancer Bad for Your Health? Casey Schwartz May 21, 2012

Historical Examples

It is evident that some sort of an antibody results from the first protein injected and that it is specific for its own antigen.
The Fundamentals of Bacteriology Charles Bradfield Morrey

So he didn’t produce an antigen—he produced a disease instead.
Pandemic Jesse Franklin Bone

Each dilution was made on the basis of the known protein concentration of the antigen.
Myology and Serology of the Avian Family Fringillidae William B. Stallcup

Injections must be made and the antigen must go into the plants, not in single doses, if you please, but by the thousands.
Northern Nut Growers Report of the Proceedings at the Twenty-First Annual Meeting Northern Nut Growers Association

In every series of tests the amount of antiserum was held constant and the amount of antigen was varied.
Myology and Serology of the Avian Family Fringillidae William B. Stallcup

It is not apparent that the nature of the antigen would affect Ehrlichs theory of the formation of antibodies.
The Fundamentals of Bacteriology Charles Bradfield Morrey

I shall not discuss the antigen or its method of administration.
Northern Nut Growers Report of the Proceedings at the Twenty-First Annual Meeting Northern Nut Growers Association

The substance within the introduced cell which acts as a stimulus (antigen) to the body cells is called an agglutinogen.
The Fundamentals of Bacteriology Charles Bradfield Morrey

The complement fixation test is like a Wassermann reaction, but the antigen should be polyvalent.
The Ethics of Medical Homicide and Mutilation Austin O’Malley

noun
a substance that stimulates the production of antibodies
n.

“substance that causes production of an antibody,” 1908, from German Antigen, from French antigène (1899), from anti- (see anti-) + Greek -gen (see -gen).

antigen an·ti·gen (ān’tĭ-jən)
n.
Any of various substances, including toxins, bacteria, and the cells of transplanted organs, that when introduced into the body stimulate the production of antibodies. Also called allergen, immunogen.
an’ti·gen’ic (-jěn’ĭk) adj.
antigen
(ān’tĭ-jən)
A substance that stimulates the production of an antibody when introduced into the body. Antigens include toxins, bacteria, viruses, and other foreign substances. Compare antibody. See Note at blood type.