noun, Biochemistry.
a glycoprotein, secreted by the gastric mucosa, that is involved in the intestinal absorption of vitamin B 12 .
(biochem) a glycoprotein, secreted by the stomach, the presence of which is necessary for the absorption of cyanocobalamin (vitamin B12) in the intestine

intrinsic factor n.
A relatively small mucoprotein secreted by the parietal cells of gastric glands and required for adequate absorption of vitamin B12 for production of red blood cells. Also called Castle’s intrinsic factor.


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