phosphodiesterase phos·pho·di·es·ter·ase (fŏs’fō-dī-ěs’tə-rās’, -rāz’)
Any of a class of enzymes that catalyze the cleaving of phosphodiester bonds, such as those between nucleotides in nucleic acids, to produce smaller nucleotide units or mononucleotides but not inorganic phosphate.


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  • Phosphodiester bond

    phosphodiester bond phos·pho·di·es·ter bond (fŏs’fō-dī-ěs’tər) n. The covalent chemical bond that holds together the polynucleotide chains of RNA and DNA by joining a specific carbon in the phosphate group in a sugar having five carobs, such as ribose, to a specific carbon in the hydroxyl group of the five-carbon sugar in the adjacent nucleotide.

  • Phosphoenolpyruvic acid

    phosphoenolpyruvic acid phos·pho·e·nol·py·ru·vic acid (fŏs’fō-ē’nôl-pī-rōō’vĭk, -pĭ-) n. The phosphoric ester of the enol form of pyruvic acid that is an intermediate in the conversion of glucose to pyruvic acid.

  • Phosphoglyceride

    phosphoglyceride phos·pho·glyc·er·ide (fŏs’fō-glĭs’ə-rīd’) n. A phospholipid containing glycerol phosphate.

  • Phosphohexose isomerase deficiency

    phosphohexose isomerase deficiency phos·pho·hex·ose isomerase deficiency (fŏs’fō-hěk’sōs’) n. See glucosephosphate isomerase deficiency.

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