long-term, pathological use of alcohol or drugs, characterized by daily intoxication, inability to reduce consumption, and impairment in social or occupational functioning; broadly, alcohol or drug addiction.
substance abuse n.
Excessive use of a potentially addictive substance, especially one that may modify body functions, such as alcohol and drugs. Also called chemical abuse.
substance abuser n.
- Substance abuse disorder
substance abuse disorder n. Any of a category of disorders in which pathological behavioral changes are associated with the regular use of substances that affect the central nervous system.
noun 1. that of which a thing consists; physical matter or material: form and substance. 2. a species of matter of definite chemical composition: a chalky substance. 3. controlled substance. 4. the subject matter of thought, discourse, study, etc. 5. the actual matter of a thing, as opposed to the appearance or shadow; reality. 6. […]
noun 1. a small peptide released upon stimulation in the nervous system and involved in regulation of the pain threshold. substance P n. A short-chain polypeptide that functions as a neurotransmitter especially in the transmission of pain impulses from peripheral receptors to the central nervous system.