HLA antigen


noun, Immunology.
1.
an antigen of the HLA group, designated by a letter (HLA-A, HLA-B, etc.) according to the chromosome locus on which the controlling HLA gene appears and additionally by a number (HLA-A1, HLA-A2, etc.) according to the order of discovery and identification.

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  • HLA

    Immunology. 1. human leukocyte antigen: any of a complex of genetically determined antigens, occurring on the surface of almost every human cell, by which one person’s cells can be distinguished from another’s and the histocompatibility and genetic likeness of any two persons can be established: the major histocompatibility antigen of humans. HLA abbr. human leukocyte […]

  • Hla complex

    HLA complex n. See major histocompatibility complex.

  • HLA gene

    noun, Immunology. 1. any of a complex of genes, located on human chromosome 6, that govern the expression of HLA.

  • Hla system

    noun 1. human leucocyte antigen system; a group of the most important antigens responsible for tissue compatibility, together with the genes that encode them. For tissue and organ transplantation to be successful there needs to be a minimum number of HLA differences between the donor’s and recipient’s tissue

  • Hla typing

    HLA typing (āch’ěl-ā’) n. A method for determining compatibility for bone marrow transplantation using the tissue of unrelated donors and recipients.


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