Acute fatty liver of pregnancy: Abbreviated AFLP, liver failure in late pregnancy, usually of unknown cause. Symptoms include nausea and vomiting, abdominal pain, yellowing of the skin and eyes (jaundice), frequent thirst (polydipsia), increased urination (polyuria), headache, and altered mental state. Laboratory features of AFLP include low blood sugar (hypoglycemia), elevated liver enzymes, and low levels of blood platelets. Untreated AFLP can cause complete liver failure, bleeding due to impaired blood clotting, and death of the mother and fetus. AFLP is treated by delivering the baby as soon as possible, often by inducing early labor. It usually subsides after delivery and does not occur in subsequent pregnancies. In some cases AFLP is associated with an abnormality of fatty-acid metabolism: a deficiency of the enzyme long-chain-3-hydroxyacyl-CoA dehydrogenease (LCHAD). The mother and father have half the normal LCHAD activity, and the fetus has no LCHAD activity. This metabolic disease in the baby’s liver causes the fatty liver disease in the mother.
- Acute glomerulonephritis Medical Definition Written by Doctors
Acute glomerulonephritis: one of a group of kidney diseases characterized by the abrupt onset of inflammation and proliferation of the glomeruli, microscopic structures within the kidney that are responsible for filtering the blood and producing urine. Acute glomerulonephritis can result in long-term damage or may resolve, depending upon the cause and severity. Acute poststreptococcal glomerulonephritis […]
- AC joint
AC joint: Acromioclavicular joint located between the acromion (a projection of the scapula that forms the point of the shoulder) and the clavicle (the collar bone). This is a gliding type of joint. The ligaments that serve to support and strengthen this joint are called the capsular; superior and inferior acromioclavicular; articular disk; and coracoclavicular […]
AC: Abbreviation for a.c. (ante cibum on a prescription); acromioclavicular (shoulder joint); antecubital (crook of elbow).
- Acute illness
Acute illness: A disease with an abrupt onset and, usually, a short course.
- Acute kidney failure
Acute renal failure.