Centimorgan (cM): A unit of measure of genetic recombination frequency. One cM is equal to a 1% chance that a marker at one genetic locus will be separated from a marker at another locus due to crossing over in a single generation. In humans, 1 cM is equivalent, on average, to 1 million base pairs. The centimorgan is named after the pioneering (and Nobel Prize winning) geneticist Thomas Hunt Morgan.
Central: At or near the center. In anatomy and medicine (as elsewhere), central is the opposite of “peripheral” which means away from the center. The word “peripheral” comes from the Greek “peripheria” (“peri-“, around or about + “pherein”, to bear, carry). A central line is an infusion tube that is located in or near the […]
- Central auditory processing disorder
Central auditory processing disorder: A neurological disorder in which a person has difficulty properly interpreting sounds received by the ears, particularly the phonemes of speech. Abbreviated CAPD. CAPD can result in difficulties with attention, speech production, and reading.
- Central core disease of muscle
Central core disease of muscle: One of the conditions that produces ‘floppy baby’ syndrome. Central core disease of muscle causes hypotonia (low muscle tone) in a newborn baby, slowly progressive muscle weakness, and muscle cramps after exercise. Muscle biopsy shows a key diagnostic finding of absent mitochondria in the center of many muscle fibers. It […]
- Central line
Central line: An infusion tube located in or near the heart, which is at the center of the circulatory system. For example, a Swan-Ganz catheter with its tip in the right atrium and ventricle of the heart is a central line.
- Central nervous system (CNS)
Central nervous system (CNS): The central nervous system is that part of the nervous system that consists of the brain and spinal cord. The central nervous system (CNS) is one of the two major divisions of the nervous system. The other is the peripheral nervous system (PNS) which is outside the brain and spinal cord. […]