Disease, Bright’s: Chronic inflammation of the blood vessels in the kidney with protein, specifically albumin, in the urine. There are a number of disorders that lead to Bright’s disease. With nothing more sophisticated than a candle and a silver spoon, the English physician Richard Bright (1789-1858) discovered protein in urine and in 1827 published his pioneering study of kidney disease.
- Disease, Brill-Zinsser
Disease, Brill-Zinsser: Recrudescence of epidemic typhus years after the initial attack. The agent that causes epidemic typhus (Rickettsia prowazekii) remains viable for many years and then when host defenses are down, it is reactivated causing recurrent typhus. The disease is named for the physician Nathan Brill and the great bacteriologist Hans Zinsser.
- Disease, Canavan
Disease, Canavan: A severe progressive inherited (genetic) disorder of the central nervous system (CNS). The signs of Canavan disease usually appear when the children are between 3 and 6 months of age. They include developmental delay (significant motor slowness), enlargement of the head (macrocephaly), loss of muscle tone (hypotonia), poor head control, and severe feeding […]
- Disease, cardiovascular
Disease, cardiovascular: Disease affecting the heart or blood vessels. Cardiovascular diseases include arteriosclerosis, coronary artery disease, heart valve disease, arrhythmia, heart failure, hypertension, orthostatic hypotension, shock, endocarditis, diseases of the aorta and its branches, disorders of the peripheral vascular system, and congenital heart disease.
- Disease, Castleman
Disease, Castleman: A disorder of lymphoid tissue (lymphadenopathy) with massive overgrowth (hyperplasia) of lymph nodes (“swollen glands”), most commonly affecting the nodes between the lungs (in the mediastinum). There are two quite different forms of Castleman’s disease. One form, found in 90% cases, is a localized kind of lympadenopathy. It usually causes no symptoms, follows […]
- Disease, cat scratch
Disease, cat scratch: A bacterial infection due to a cat scratch seen most often today in people with HIV. The disease characteristically presents with swollen lymph nodes (lymphadenitis), sore throat, fatigue, and fever, chills, sweats, vomiting, loss of appetite, and weight loss. There is usually a little bump (a papule) which may be pus-filled (a […]