Familial lung cancer
Familial lung cancer: Lung cancer that recurs in families. Lung cancer can occur sporadically in people with no known family history of lung cancer or it can occur in two or more members of the same family and constitute familial lung cancer.
A gene for familial lung cancer is on the long (q) arm of chromosome 6 in a region that runs from chromosome band 6q23 through band 6q25. People carrying this gene for familial lung cancer appear unusually sensitive to tobacco smoke. Even a small amount of smoking may be enough to cause lung cancer. By contrast, the risk of lung cancer rises with the amount of smoking in people who do not carry this gene.
Read Also:
- Familial Mediterranean fever (FMF)
Familial Mediterranean fever (FMF): An inherited disorder featuring short recurring crises of severe abdominal pain and bouts of fever. Other symptoms include arthritis, chest pain from inflammation of the lung cavity, and skin rashes. Between attacks, the patient seems healthy. Amyloidosis (the abnormal deposition of a particular protein, called amyloid, in various tissues of the […]
- Familial Parkinson disease type 1
Familial Parkinson disease type 1: A familial form of Parkinson disease inherited in an autosomal dominant manner due to mutation in the alpha-synuclein gene (SNCA) on chromosome 4q21. Also known as PARK1.
- Familial Parkinson disease type 10
Familial Parkinson disease type 10: A familial form of Parkinson disease inherited in an autosomal dominant manner due to a gene on chromosome 1p. Also known as PARK10.
- Familial Parkinson disease type 11
Familial Parkinson disease type 11: A familial form of Parkinson disease inherited in an autosomal dominant manner due to a gene on chromosome 2q. Also known as PARK11.
- Familial Parkinson disease type 2
Familial Parkinson disease type 2: A familial form of Parkinson disease inherited in an autosomal recessive manner due to mutation in the gene encoding parkin on chromosome 6q25.2-q27. Also known as PARK2.