Genoplasty: A technology that uses the repair mechanisms normally present in cells to repair gene defects.
In genoplasty, a short oligonucleotide fragment is introduced into the cell to simulate a normal DNA sequence and this deceives the cell into repairing itself. The sequence of the gene itself is thus changed permanently.
Genoplasty is different from gene therapy in which a normal gene is inserted into the cell.
Genotoxin: A poisonous substance which damages DNA. A genotoxin can cause mutations in DNA (and so be a mutagen), it can trigger cancer (and so be a carcinogen), or it can cause a birth defect (and so be a teratogen). From geno- (genetic) + toxin (poison) = a genetic poison.
Genotype: The genetic constitution (genome) of a cell, an individual, or an organism. The genotype is distinct from the expressed features, or phenotype, of the cell, individual, or organism. The genotype of a person is that person’s genetic makeup. It can pertain to all genes or to a specific gene.
Genu: The Latin word for the knee. When the knee is referred to in medicine, it is just called the knee. However, the word “genu” is also used in medicine as in: genu recurvatum (hyperextension of the knee), genu valgum (knock knee) and genu varum (bowleg). The knee (or genu, if you are into Latin) […]
Gephyrophobia: An abnormal and persistent fear of crossing bridges. Sufferers of this phobia experience undue anxiety even though they realize their fear is irrational. Their fear may result partly from the fear of enclosure (claustrophobia) or the fear of heights (acrophobia). Phobic drivers may worry about being in an accident in busy traffic or losing […]
Gerascophobia: An abnormal and persistent fear of growing old. Sufferers of this fear experience undue anxiety about aging even though they may be in good health–physically, economically and otherwise. They may worry about the loss of their looks, the loss of independence, inactivity after retirement, impaired mobility, the onset of disease, and confinement in a […]