Granulomatosis, Wegener’s


An inflammatory disease of small arteries and veins (vasculitis) that classically involves vessels supplying the tissues of the lungs, nasal passages (sinuses), and kidneys.

Symptoms include fatigue, weight loss, fevers, shortness of breath, bloody sputum, joint pains, and sinus inflammation, sometimes with nasal ulcerations and bloody nasal discharge. Wegener’s granulomatosis most commonly affects young or middle-aged adults.

The diagnosis of Wegener’s granulomatosis is confirmed by finding evidence of vasculitis and abnormal cellular formations called granulomas on biopsy of tissue involved by the inflammatory process.

Wegener’s granulomatosis is a serious disease. Without treatment, it can be fatal within months. Treatment is directed toward stopping the inflammation process by suppressing the immune system.

Read Also:

  • Granulomatous colitis

    Involvement of the large intestine (colon) only is called Crohn’s colitis or granulomatous colitis, while involvement of the small intestine alone is called Crohn’s enteritis. The most common part of the small intestine to be affected by Crohn’s disease is the last portion, called the ileum. Active disease in this area is termed Crohn’s ileitis. […]

  • Grapefruit diet

    The Grapefruit diet is a weight loss plan that incorporates eating half a grapefruit with each meal and following a severely restrictive low-calorie diet. Like many other “fad” diets, rumors have circulated that this diet is associated with a major medical center, but this is untrue. The grapefruit diet has not been recommended by medical […]

  • Graves' disease

    Hyperthyroidism (the presence of too much thyroid hormone), Ophthalmopathy specifically involving exophthalmos (protrusion of the eyeballs), Dermopathy with skin lesions. Take the Ankylosing Spondylitis Quiz Myths and Facts About Back Pain The ophthalmopathy can cause sensitivity to light and a feeling of “sand in the eyes.” With further protrusion of the eyes, double vision and […]

  • Gray

    Milligray. Gray is, of course, also a hue between black and white.

  • Gray baby syndrome

    A syndrome due to toxicity of the antibiotic chloramphenicol in the newborn, especially the premature newborn, because of lack the necessary liver enzymes to metabolize this drug. Chloramphenicol accumulates in the baby, causing hypotension (low blood pressure), cyanosis (blue coloring of lips, nail beds, and skin from lack of oxygen in the blood), and often […]


Disclaimer: Granulomatosis, Wegener's definition / meaning should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional. All content on this website is for informational purposes only.