Hemophilia B


Hemophilia due to deficiency of coagulation factor IX in the blood, which results in prolonged oozing after minor and major injuries, tooth extractions, or surgery. There is renewed bleeding after the initial bleeding has stopped. The gene for hemophilia B is on the X chromosome, so males are affected and females carry the gene. About 10 percent of carrier females are at risk for bleeding. Treatment involves administration of blood products that introduce clotting factor IX and replace lost blood. Also called Christmas disease (named for the first patient with the disease to be studied in detail).

Read Also:

  • Hemophilia carrier

    A female carrying a mutant gene for hemophilia on one of her two X chromosomes and a normal allele on her other X chromosome. Hemophilia carriers have concentrations of clotting factor VIII or IX of about 50% of normal and, hence, decreased ability to clot their blood. However, if they have a clinical bleeding tendency, […]

  • Hemoptysis

    Spitting up blood or blood-tinged sputum from the respiratory tract. Hemoptysis occurs when tiny blood vessels that line the lung airways are broken. Hemoptysis can be harmless such as from irritated bronchial tubes with bronchitis, or be serious such as from cancer of the lung.

  • Hemorrhage

    Bleeding or the abnormal flow of blood. A hemorrhage may be “external” and visible on the outside of the body or “internal,” where there is no sign of bleeding outside the body. Bleeding from a cut on the face is an external hemorrhage. Bleeding into the spleen or liver are examples of internal hemorrhage. The […]

  • Hemorrhage, subarachnoid

    Bleeding within the head into the space between two membranes that surround the brain. The bleeding is beneath the arachnoid membrane and just above the pia mater. (The arachnoid is the middle of three membranes around the brain while the pia mater is the innermost one.) The subarachnoid space is a potential space. It is […]

  • Hemorrhagic

    Pertaining to bleeding or the abnormal flow of blood. The patient may have an internal hemorrhagic problem that is not be visible or the patient may have an external hemorrhagic problem that is therefore visible on the outside of the body. The term “hemorrhagic” comes from the Greek “haima,” blood + rhegnumai,” to break forth […]


Disclaimer: Hemophilia B definition / meaning should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional. All content on this website is for informational purposes only.