Holandric inheritance
Inheritance of genes on the Y chromosome. Because only males normally have Y chromosomes, Y-linked genes can only be transmitted from father to son.
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- Hole, macular
A hole in the macula, the tiny oval area made up of millions of nerve cells located at the center of the retina responsible for sharp, central vision. The eye contains a jelly-like substance called the vitreous. Shrinking of the vitreous usually causes the hole. As a person ages, the vitreous becomes thicker and stringier […]
- Holmes, Oliver Wendell, Sr.
“If every drug from the vegetable, animal, and mineral kingdom were to disappear from the market, a body of enlightened men, organized as a distinct profession, would be required just as much as now, whose province should be to guard against the causes of disease, to eliminate them if possible when still present . . […]
- Holoprosencephaly
This relatively common birth defect of the brain, often also affects facial features, causing closely spaced eyes, small head size, and sometimes clefts of the lip and roof of the mouth. Not all individuals with holoprosencephaly (HPE) are affected to the same degree, even in families where more than one individual has this predisposition. The […]
- Holt-Oram syndrome
A genetic syndrome characterized by the combination of heart disease and malformations of the upper limb. The heart defect is usually an atrial septal defect (ASD) and, less often, a ventricular septal defect (VSD), although other cardiovascular malformations have been reported. The upper limb malformations most often affect the forearm and thumb. The thumb may […]
- Holter monitor
A type of portable heart monitor that is a small electrocardiogram (EKG) device worn in a pouch around the neck or waist. A Holter monitor keeps a record of the heart rhythm, typically over a 24-hour period, and the patient keeps a diary of activities and symptoms. The EKG recording is then correlated with the […]