Isocellular
Composed of cells of the same size and type. Isocellular is a Greek-Latin hybrid term compounded from the Greek iso- meaning “equal or like” + the Latin cellula, the diminutive of cella, a storeroom.
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- Isochromosome
An abnormal chromosome that has two identical arms due to duplication of one arm and loss of the other. Isochromosomes are found in tumors and in some girls with Turner syndrome.
- Isochromosome 17q
An abnormal chromosome 17 with two identical long (q) arms due to duplication of the long arm and loss of the short arm. Isochromosome 17q is the most common isochromosome in cancer. It plays an important role in tumor development and progression. Hematologic malignancies such as chronic myeloid leukemia (CML) with isochromosome 17q carry a […]
- Isodisomy
A remarkable situation in which both chromosomes in a pair are from one parent only. Isodisomy causes some birth defects and is suspected to play a role in cancer. Also known as uniparental disomy.
- Isoflavone
A type of plant estrogen (phytoestrogen) found chiefly in soybeans.
- Isoform
A protein that has the same function as another protein but which is encoded by a different gene and may have small differences in its sequence. For example, transforming factor beta (TGF-B) exists in three versions, or isoforms (TGF-B1, TGF-B2, and TGF-B3), each of which can set off a signaling cascade that starts in the […]