Keratitis-ichthyosis-deafness syndrome


An inherited disorder that is characterized by keratitis (gradual destruction of the cornea of the eye, sometimes leading to blindness), ichthyosis (localized areas of disfiguring reddish thickened skin), and deafness from birth. Abbreviated KID syndrome. Another characteristic feature of KID syndrome is thin or absent scalp hair. Some patients develop cancer of the tongue, and some have subtle abnormalities of the nervous system. KID syndrome is inherited in an autosomal dominant manner and is usually due to mutation in the connexin-26 gene (located on chromosome 13).

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  • Kerato-

    Prefix that can refer either to the cornea (as in keratitis and keratocornea) or to “horny” tissue (as in keratin and keratosis).

  • Keratoconjunctivitis

    Inflammation of the eye that involves both the cornea and conjunctiva. Keratoconjunctivitis can occur due to abrasion trauma, infection, and underlying diseases such as Sjogren’s syndrome and lupus.

  • Keratoconjunctivitis sicca

    also known as dry eye syndrome or keratitis sicca, a condition characterized by the inability of the eye to produce sufficient tears to keep it moist. It is more common in older adults and in some cases may be associated with underlying diseases such as Sjogren’s syndrome, rheumatoid arthritis, and lupus. Vision disturbances and loss […]

  • Keratoconus

    A cone-shaped cornea, with the apex of the cone being forward. Keratoconus causes distorted vision. Also known as conical cornea. Treatment of keratoconus depends on the severity of the condition. Treatment options include eyeglasses, rigid contact lenses, and corneal transplantation, and combinations of these.

  • Keratodermia blennorrhagicum

    A skin disease that occurs in patients with reactive arthritis (formerly Reiter’s syndrome). Abbreviated KB. Classically, the areas of the skin that are involved are the palms of the hands and the soles of the feet, although other body surfaces may also be affected. The inflammation of the skin can come and go. When the […]


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