early localized disease with skin inflammation; early disseminated disease with heart and nervous system involvement, including palsies and meningitis; and late disease, featuring motor and sensory nerve damage and brain inflammation and arthritis. Within hours to weeks of the tick bite, an expanding ring of unraised redness develops, with an outer ring of brighter redness and a central area of clearing, giving it the appearance of a bull’s-eye. The redness of the skin is often accompanied by generalized fatigue, muscle and joint stiffness, swollen glands, and headache. Early treatment with antibiotics is the best strategy for preventing major problems due to Lyme disease. Further prevention of Lyme disease involves avoiding areas where ticks are common, wearing protective clothing and lotion, and immediately removing any ticks from the body. Interestingly, Lyme disease only became apparent in 1975, when mothers of a group of children who lived near each other in Lyme, Connecticut, made researchers aware that their children were all diagnosed with rheumatoid arthritis. This unusual grouping of illness that appeared to be rheumatoid eventually led researchers to the identification of the bacterial cause of Lyme disease in 1982.
The almost colorless fluid that travels through the lymphatic system, carrying cells that help fight infection and disease.
- Lymph node
One of many small, bean-shaped organs located throughout the lymphatic system. The lymph nodes are important in the function of the immune response and also store special cells that can trap cancer cells or bacteria that are traveling through the body through the lymph. Also known as lymph gland.
- Lymph node, sentinel
The first lymph node to receive lymphatic drainage from a tumor. The sentinel node for a given tumor is found by injecting a tracer substance around the tumor. This substance then travels through the lymphatic system to the sentinel node. The tracer substance may be a blue dye that can be tracked visually or a […]
- Lymphadenitis, regional
Cat scratch disease, a mild flu-like infection, with swollen lymph nodes (lymphadenitis) and mild fever of short duration, due to cat scratches, especially from kittens. There is usually a little bump (a papule) which may be pus-filled (a pustule) at the site of the scratch. The infection is self-limited and usually goes away by itself […]
Abnormally enlarged lymph nodes. Commonly called swollen glands.