Pelizaeus-Merzbacher-like disease
A disease that is virtually identical to Pelizaeus-Merzbacher disease (PMD) but without a mutation in the PLP1 gene that causes PMD. Both PMD and Pelizaeus-Merzbacher-like disease (PMLD) are characterized by rapid, involuntary movements of the eye (nystagmus), impaired motor development, ataxia, and difficulty articulating. Some patients with PMLD have diverse mutations in a gene called GJP12 which encodes the gap junction protein 12 (also known as connexin 46.6) that plays a key role in central myelination and is involved in peripheral myelination.
Read Also:
- Pellagra
meat (pork fatback); molasses; and meal (cornmeal). Today pellagra continues to be a problem in developing countries where there is significant malnutrition or where niacin-deficient foods such as corn and rice are the primary sources of nutrition. The puzzle of pellagra was solved by Dr. Joseph Goldberger. Dr. Goldberger was assigned in 1914 by the […]
- Pelvic
Having to do with the pelvis, the lower part of the abdomen, located between the hip bones.
- Pelvic congestion syndrome
chronic pelvic pain caused by ovarian and internal iliac varices.
- Pelvic exam
An examination of the organs of the female reproductive system. In a pelvic exam, a speculum (an instrument for opening and widening certain passages of the body) is used to open the vagina and aid in visualizing the uterine cervix. A sample of cells may be taken off the surface of the cervix for a […]
- Pelvic inflammatory disease (PID)
Ascending infection of the female upper genital tract (the female structures above the cervix). PID is the most common and serious complication of sexually transmitted diseases (STDs), aside from AIDS, among women. The signs and symptoms of PID include fever, foul-smelling vaginal discharge, extreme pain, including pain during intercourse, and vaginal bleeding. PID can scar […]