Phosphatase, alkaline


An enzyme that liberates phosphate under alkaline conditions and is made in liver, bone, and other tissues. Alkaline phosphatase can be measured in a routine blood test. Abnormally high serum levels of alkaline phosphatase may indicate bone disease, liver disease, or bile duct obstruction.

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  • Phosphate

    A form of phosphoric acid. Calcium phosphate makes bones and teeth hard.

  • Phospholipase

    An enzyme that catalyzes the splitting of a phospholipid molecule by the addition of water. Also called a lecithinase. There are a number of phospholipases. They are grouped on the basis of the specific chemical bond they split. The phospholipases include phospholipase A1 (PLA1), phospholipase A2 (PLA2), phospholipase C, and phospholipase D.

  • Phosphorus

    An essential element in the diet and a major component of bone.

  • Phosphorylation

    A biochemical process that involves the addition of phosphate to an organic compound. Examples include the addition of phosphate to glucose to produce glucose monophosphate and the addition of phosphate to adenosine diphosphate (ADP) to form adenosine triphosphate (ATP). Phosphorylation is carried out through the action of enzymes known as phosphotransferases or kinases.

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