Pregnancy-associated malaria


A specific syndrome that occurs only in pregnant women and that is characterized by the accumulation in the placenta of red blood cells containing the malarial parasite. Pregnancy-associated malaria causes low birthweight and maternal anemia. Therefore, it is associated with substantial rates of morbidity (disease) and mortality (death) for both the mother and baby.

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    Abbreviated as PAPPA or PAPP-A. A large zinc-binding protein that acts as an enzyme, specifically a metallopeptidase. The gene for PAPPA is in chromosome band 9q33.1. PAPPA has been used in prenatal genetic screening and studies of atherosclerosis. Women with low blood levels of PAPPA at 8 to 14 weeks of gestation have an increased […]

  • Pregnant

    The state of carrying a developing fetus within the body. The word “pregnant” comes from the Latin pre- meaning before + (g)natus meaning birth = before (giving) birth. The word “prenatal” has exactly the same origin.

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