Norvir), and they are used primarily in HIV/AIDS treatment. They are taken as part of a multi-drug cocktail and have been shown to be capable of significantly reducing the level of HIV virus in the blood. Side effects associated with protease inhibitors include lipodystrophy syndrome, in which the face, arms, and legs become thin due to loss of subcutaneous fat; the skin becomes dry; weight loss occurs; and abnormal deposits of fat occur. Some strains of HIV may be resistant to protease inhibitors.
One of the three nutrients used as energy sources (calories) by the body. Proteins are essential components of the muscle, skin, and bones. Proteins and carbohydrates each provide 4 calories of energy per gram, whereas fats provide 9 calories per gram.
- Protein C
A vitamin K’dependent protein in plasma that enters into the cascade of biochemical events leading to the formation of blood clots.
- Protein C deficiency
Protein C is a protein in plasma that enters into the cascade of biochemical events leading to the formation of a clot. Deficiency of protein C results in thrombotic (clotting) disease and excess platelets with recurrent thrombophlebitis (inflammation of the vein that occurs when a clot forms). The clot can break loose and travel through […]
- Protein kinase A
An enzyme system that is activated by cyclic adenosine monophosphate (cAMP) and that catalyzes the activity of intracellular proteins. There are two isozymes of protein kinase A, type I and type II. Also known as cAMP-dependent protein kinase and cyclic AMP-dependent protein kinase.
- Protein malnutrition
Insufficient intake of nitrogen-containing food (protein) to maintain a nitrogen balance or nitrogen equilibrium. Children are particularly prone to develop protein malnutrition. To grow, children have to consume enough nitrogen-containing food (protein) to maintain a positive nitrogen balance, whereas adults need only be in nitrogen equilibrium. See also kwashiorkor.