Silver bullet


The Silver Bullet in Medicine.

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  • Simian crease

    A single transverse crease in the palm, a minor variation associated with Down syndrome (trisomy 21) and a number of chromosomal and other abnormalities. Also called a four-finger crease; single palmar flexion crease; single upper palm crease.

  • Single base change

    A change in which a single base in the DNA differs from the usual base at that position. These single base changes are also called SNPs or “snips.” Millions of SNP’s have been cataloged in the human genome. Some SNPs such that which causes sickle cell are responsible for disease. Other SNPs are normal variations […]

  • Single gene disease

    Any genetic disorder caused by a change affecting only one gene. There are thousands of single-gene diseases including achondroplasia, cystic fibrosis, hemophilia, Huntington disease, muscular dystrophy, and sickle cell disease . Single-gene diseases usually follow simple Mendelian patterns of inheritance — autosomal dominant, an autosomal recessive, or an X-linked. Single gene diseases are as opposed […]

  • Single nucleotide polymorphism

    A change in which a single base in the DNA differs from the usual base at that position. Abbreviated SNP and pronounced snip. Millions of SNP’s have been cataloged in the human genome. Some SNPs are responsible for disease such as the SNP responsible for sickle cell disease. Many other SNPs are normal variations in […]

  • Single palmar flexion crease

    Simian crease. Single upper palm crease Single transverse palmar line Four-finger line Single palmar flexion line Single upper palm line


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