A syndrome of unknown origin, mainly affecting young children, that causes fever, reddening of the eyes (conjunctivitis), lips and mucous membranes of the mouth, ulcerative gum disease (gingivitis), swollen glands in the neck (cervical lymphadenopathy), and a rash that is raised and bright red (maculoerythematous) in a glove-and-sock fashion over the skin of the hands and feet which becomes hard, swollen (edematous), and peels off. Also called “mucocutaneous lymph node syndrome,” a name that is quite descriptive because the disease is characterized by the typical changes in the mucus membranes that line the lips and mouth and by the enlarged and tender lymph glands. The syndrome was first described in the late 1960’s in Japan by the pediatrician Tomisaku Kawasaki.
- Syndrome, keratitis-ichthyosis-deafness
See Keratitis-ichthyosis-deafness syndrome.
- Syndrome, KID
Acronym for the Keratitis- Ichthyosis-Deafness syndrome, a genetic disorder. See Keratitis-ichthyosis-deafness syndrome.
- Syndrome, Kimmelstiel-Wilson
Diabetic nephropathy (kidney disease). Kimmelstiel-Wilson syndrome is a kidney condition associated with long-standing diabetes. It affects the network of tiny blood vessels (the microvasculature) in the glomerulus, a key structure in the kidney that is composed of capillary blood vessels and which is critically necessary for the filtration of the blood. Features of Kimmelstiel-Wilson syndrome […]
- Syndrome, Klippel-Trenaunay-Weber (KTW)
A congenital malformation syndrome characterized by the triad of asymmetric limb hypertrophy, hemangiomata, and nevi. “Asymmetric limb hypertrophy” is enlargement of one limb and not the corresponding limb on the other side, the enlarged limb being 3 times more likely to be a leg than an arm in KTW; and the limb enlargement is of […]
- Syndrome, Kostmann
severe congenital neutropenia (SCN). severe congenital neutropenia was first clearly described by Kostmann in 1956. It is now known to be caused by a defect in a gene on chromosome 1 (in 1p35-p34.3) that codes for what is called the granulocyte colony-stimulating factor receptor (GCSFR). Treatment with recombinant human granulocyte colony-stimulating factor (GCSF) elevates the […]