Therapy, gene


adenosine deaminase (ADA) deficiency.

In late October of 1999 the U.S. moved to require the disclosure of the results of gene therapy. The move by the Recombinant DNA Advisory Committee came 6 weeks after the death of an 18-year-old Arizona man, Jesse Gelsinger, who was apparently the first person to die as a result of gene therapy. Researchers at the University of Pennsylvania, where Mr. Gelsinger received gene therapy, were prompt to report his death and talked of it publicly. Although there was no evidence that any other patients had died as a result of receiving gene therapy, the committee (which reports to the director of the National Institutes of Health) was concerned that some scientists and companies had not always been so forthcoming with information about side effects experienced by gene therapy patients.

Read Also:

  • Therapy, hormone replacement (HRT)

    The combination therapy of estrogen plus a progestogen. Formerly, hormone replacement therapy (HRT). Estrogen therapy (ET) is used to treat the symptoms of menopause. It reduces or stops the short-term changes of menopause such as hot flashes, disturbed sleep, and vaginal dryness. Estrogen therapy can prevent osteoporosis, a consequence of lowered estrogen levels. Vaginal estrogen […]

  • Therapy, human gene

    Insertion of normal DNA directly into cells to correct a genetic defect. The treatment of disease by replacing, altering, or supplementing a gene that is absent or abnormal and whose absence or abnormality is responsible for a disease. In studies of gene therapy for cancer, for example, researchers are trying to bolster the body’s natural […]

  • Therapy, pulmonary

    Exercises and treatments designed to help patients maintain and recover lung function, such as with cystic fibrosis and after surgery. Also used for COPD and asthma.

  • Therapy, respiratory

    Exercises and treatments designed to help patients maintain and recover lung function, such as with cystic fibrosis and after surgery. Also used for COPD and asthma.

  • Therapy, testosterone replacement

    The practice of giving testosterone to men when the testes do not produce enough testosterone. This may be due to absence, injury, or disease. Over supplementation has serious side effects. Testosterone is available in oral, IV, patch forms, and implantable pellets. There is no known indication for testosterone in women, it was considered as a […]


Disclaimer: Therapy, gene definition / meaning should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional. All content on this website is for informational purposes only.