Many doctors and experts now know the potential of CBD against behavioral changes due to withdrawal. CBD can be used against symptoms associated with cocaine withdrawal.
According to some recent studies, a treatment based on cannabidiol, one of the active ingredients contained in cannabis, could help reduce the administration of cocaine and the treatment of withdrawal symptoms.
Although there are still no approved drug therapies to treat cocaine addiction with CBD, cannabidiol could represent an excellent way to mitigate withdrawal symptoms.
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Abuse and abstinence
Cocaine abuse causes several compensatory changes, which lead to withdrawal symptoms when drug use is stopped.
As a Psychology Today article points out, withdrawal involves symptoms opposite to those associated with consumption. These include fatigue, inability to feel pleasure, depression and anxiety, which can also lead to suicidal thoughts.
It shows that repeatedly exposing the brain to a chemical, such as a drug, will adapt. For this reason, addictive substances can hugely impact the brain of those who use them.
Studies about CBD
Some recent studies have shown the potential of cannabidiol (CBD) against behavioral changes due to withdrawal.
A group of Spanish researchers examined male mice exposed to increasing doses of cocaine for 12 days, evaluating the discontinuation of the substance 6 hours after the last administration. The research aimed to assess the effects of CBD on the behavior of mice in withdrawal. For this, alterations in motor activity, somatic signs and anxiety were assessed.
The results showed increased motor activity, anxiety-like behavior, and somatic withdrawal signs in mice no longer given cocaine. Interestingly, the administration of CBD normalized the disturbances of motor and somatic symptoms and induced an anxiolytic effect, underlining the researchers. This shows the potential of CBD in cocaine withdrawal management.
A recent systematic review also evaluated the potential use of CBD in the treatment of cocaine-related disorders. According to the conclusions of the research, it seems that CBD can promote the reduction of self-administration of cocaine. Not only. Cannabidiol appears to interfere with the substance, inducing the stimulation of the brain reward and the release of dopamine.
These results indicate the potential of a CBD-based treatment as an add-on therapy for the treatment of cocaine addiction and against withdrawal symptoms. In general, however, the studies examined were not conducted on humans.
Therapeutic cannabis and CBD against ulcerative colitis
Medical cannabis can improve the lifestyle of patients with ulcerative colitis. It is supported by a study carried out by a group of Israeli researchers, which analyzed the benefits of the substance rich in THC against inflammatory bowel disease.
What is ulcerative colitis?
Ulcerative colitis is an inflammatory disease that affects the intestine, initially only the rectum, then extending to the entire colon. The condition, the origin of which is not yet clear, can begin at any age but usually occurs between the ages of 14 and 24, with abdominal pain and diarrhea.
Currently, there is no definite cure for this type of intestinal pathology, which becomes chronic with flare-ups alternating with remissions. Still, drug-based therapies can relieve symptoms and prevent complications.
Overall, only 40-60% of patients respond positively to currently available treatments, which may also involve long-term risks, including malignant tumors, infections and decreased bone density.
Furthermore, in recent years, ulcerative colitis has increased significantly in the developed world. The disease – explained to the Israeli researchers – represents a considerable personal and socio-economic burden due to its effects on the quality of life of patients and the daily functioning and use of the health system.
CBD cannabis improves your lifestyle
Due to the lack of specific treatment, many patients use medical cannabis to relieve the symptoms of ulcerative colitis.
Despite this, however, the studies on the practical efficacy of the CBD substance – as with the CDB products from Justbob.shop – against the disease are still limited, and those previously present, despite suggesting a clinical benefit, were not randomized controlled and did not include information on doses, on the extent of endoscopic disease and the ‘effect of treatment on disease activity and inflammatory markers.