either of an identical pair of Y -shaped polypeptides that, together with the light chains, constitute the antibody molecule.
(immunol) a type of polypeptide chain present in an immunoglobulin molecule
heavy chain heav·y chain (hěv’ē)
One of a pair of polypeptide chains of high molecular weight that are components of an immunoglobin and that serve as the binding sites for antigens. They are separated into five types: gamma, alpha, delta, epsilon, and mu.
The larger of the two types of polypeptide chains in an immunoglobulin molecule. A heavy chain consists of an antigen-binding portion having a variable amino acid sequence, and a constant region that is different for each class of imunoglobulin. Each heavy chain is one of a Y-shaped identical pair and is attached along its variable region to a smaller light chain. Compare light chain.
- Heavy chain disease
heavy chain disease n. Any of several disorders of lymphocytes characterized by the presence of high-molecular-weight polypeptides, especially gamma-globulins, in serum and urine and by symptoms similar to those of malignant lymphoma.
- Heavy click time
noun phrase The moment when television viewers most likely change the channel: They ponder ”pod positioning” and ”heavy click time” (the moments when most viewers reach for their remote controls) (1990s+ Television)
noun 1. thick cream having a high percentage of butterfat.
noun 1. a naval cruiser having 8-inch (20.3-cm) guns as its main armament.