[hee-muh-fil-ee-uh, -feel-yuh, hem-uh-] /ˌhi məˈfɪl i ə, -ˈfil yə, ˌhɛm ə-/
any of several X-linked genetic disorders, symptomatic chiefly in males, in which excessive bleeding occurs owing to the absence or abnormality of a clotting factor in the blood.
1854 (in anglicized form hæmophily), from German hämophile, coined 1828 by German physician Johann Lucas Schönlein (1793-1864), from Greek haima “blood” (see -emia) + philia “to love” (see -philia), here with a sense of “tendency to.”
hemophilia he·mo·phil·i·a (hē’mə-fĭl’ē-ə, -fēl’yə)
Any of several hereditary blood-coagulation disorders, manifested almost exclusively in males, in which the blood fails to clot normally because of a deficiency or an abnormality of one of the clotting factors.
Any of several hereditary coagulation disorders, seen almost exclusively in males, in which the blood fails to clot normally because of a deficiency or an abnormality of one of the clotting factors.
hemophilia [(hee-muh-fil-ee-uh, hee-muh-feel-yuh)]
A hereditary disease caused by a deficiency of a substance in the blood that aids in clotting. Hemophiliacs can bleed to death even from small cuts and bruises, because their blood has largely lost the ability to clot.
Note: Queen Victoria of Britain, whose descendants have been kings and queens of several countries in Europe, carried the gene for hemophilia, which has turned up repeatedly in royal families since her lifetime. Her great-grandson, the heir to the throne of Russia, suffered from the disease, and his parents fell under the influence of the monk Grigori Rasputin in hopes of a miraculous cure. The resulting chaos in the government of Russia helped bring on the Russian Revolution and the establishment of the Soviet Union.
- Hemophilia a
hemophilia A n. Hemophilia due to deficiency of factor VIII, characterized by prolonged clotting time, decreased formation of thromboplastin, and diminished conversion of prothrombin.
- Hemophilia b
hemophilia B n. A clotting disorder of blood resembling hemophilia A, caused by hereditary deficiency of factor IX. Also called Christmas disease.
[hee-muh-fil-ee-ak, -fee-lee-, hem-uh-] /ˌhi məˈfɪl iˌæk, -ˈfi li-, ˌhɛm ə-/ noun 1. Also, hemophile. a person having . adjective 2. (def 1). 1896 (adj.); 1897 (n.)., from hemophilia. Perhaps modeled on French hémophilique (1880). hemophiliac he·mo·phil·i·ac (hē’mə-fĭl’ē-āk’, -fē’lē-) n. A person who is affected with hemophilia.
[hee-muh-fil-ik, hem-uh-] /ˌhi məˈfɪl ɪk, ˌhɛm ə-/ adjective 1. characteristic of or affected by . 2. (of bacteria) developing best in a culture containing blood, or in blood itself. hemophilic he·mo·phil·ic (hē’mə-fĭl’ĭk) adj.