Magnum-opus



noun
1.
a great work, especially the chief work of a writer or artist: Proust’s magnum opus is Remembrance of Things Past.
noun
1.
a great work of art or literature, esp the greatest single work of an artist

“masterpiece, a person’s greatest work,” Latin, literally “great work” (see magnum + opus).
magnum opus [(mag-nuhm oh-puhs)]

The most important work in a person’s career, especially in literature, art, or scholarship: “Moby Dick was Melville’s magnum opus.” From Latin, meaning “great work.”

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