a severe anemia caused by the diminution or absence of stomach acid secretion, with consequent failure of the gastric mucosa to secrete the intrinsic factor necessary for the absorption of vitamin B 1 2 , characterized by a great reduction in the number of red blood cells and an increase in their size.
pernicious anemia n.
A severe form of anemia most often affecting older adults, caused by failure of the stomach to absorb vitamin B12 and characterized by abnormally large red blood cells, gastrointestinal disturbances, and lesions of the spinal cord. Also called Addison’s anemia, malignant anemia.
[per-nish-uh s] /pərˈnɪʃ əs/ adjective 1. causing insidious harm or ruin; ruinous; injurious; hurtful: pernicious teachings; a pernicious lie. 2. deadly; fatal: a pernicious disease. 3. Obsolete. evil; wicked. /pəˈnɪʃəs/ adjective 1. wicked or malicious: pernicious lies 2. causing grave harm; deadly adj. early 15c., from Middle French pernicios (13c., Modern French pernicieux) and directly […]
- Pernicious vomiting
pernicious vomiting n. Uncontrollable vomiting.
[per-nik-i-tee] /pərˈnɪk ɪ ti/ adjective 1. . /pəˈnɪkɪtɪ/ adjective (informal) 1. excessively precise and attentive to detail; fussy 2. (of a task) requiring close attention; exacting adj. 1808 (pernicktie, in Jamieson), “precise, fastidious,” extended form of Scottish pernicky, of uncertain origin, perhaps somehow from particular. adjective Overfastidious; finical; fussy [first form 1905+, second 1814+; fr […]
[Bulgarian per-nik] /Bulgarian ˈpɛr nɪk/ noun 1. former name of . /Bulgarian ˈpɛrnik/ noun 1. an industrial town in W Bulgaria, on the Struma River. Pop: 84 000 (2005 est) Former name (1949–62) Dimitrovo