(formerly) the mainland of America adjacent to the Caribbean Sea, especially the area between the mouth of the Orinoco River and the Isthmus of Panama.
the Caribbean Sea: the route of the Spanish treasure galleons and a former haunt of pirates.
Spanish Main
the mainland of Spanish America, esp the N coast of South America from the Isthmus of Panama to the mouth of the Orinoco River, Venezuela
the Caribbean Sea, the S part of which in colonial times was the route of Spanish treasure galleons and the haunt of pirates


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