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out of the right or proper course, order, or condition; improperly; wrongly; astray:
Did I speak amiss?
improper; wrong; faulty:
I think something is amiss in your calculations.
take amiss, to be offended at or resentful of (something not meant to cause offense or resentment); misunderstand:
I couldn’t think of a way to present my view so that no one would take it amiss.
Contemporary Examples

From the start of the investigation, there were signs that something was amiss.
Lesley Herring: The Hollywood Murder Case With No Body Christine Pelisek March 27, 2013

He did not suspect anything was amiss until he returned home that evening and found them gone.
How ISIS’s Colorado Girls Were Caught Michael Daly October 21, 2014

Brega offered no hint that anything was amiss, basically because Libyans were barred from living there.
Happy Birthday from Hizbollah! Neil MacFarquhar May 5, 2009

All of this happened in daylight, and controllers were aware that something was amiss.
The Botched Hunt for Malaysia Airlines Flight 370 Clive Irving March 11, 2014

There seems to be a prevalent feeling that something is amiss at Apple.
Apple’s Earnings Show the Company Is Still Thriving Edward Ferguson July 22, 2013

Historical Examples

None knew that anything was amiss, as he stood that day at the bedside of the sufferer whom his skill had saved.
Marie Tarnowska Annie Vivanti

Mrs. Menotti tried to detain him; she could not understand what was amiss.
Rico and Wiseli Johanna Spyri

A young specimen, without rouge or moustache, would not be amiss.
The Widow Barnaby Frances Trollope

It may not be amiss to remark that I have never eaten a blackberry since.
A Woman Tenderfoot Grace Gallatin Seton-Thompson

Somewhere about midnight thereafter, Bertric woke with a start which roused me, so that I sat up and asked what was amiss.
A Sea Queen’s Sailing Charles Whistler

adverb
in an incorrect, inappropriate, or defective manner
take something amiss, to be annoyed or offended by something
adjective
(postpositive) wrong, incorrect, or faulty
adv.

mid-13c., amis “off the mark,” also “out of order,” literally “on the miss,” from a “in, on” (see a- (1)) + missen “fail to hit” (see miss (v.)). To take (something) amiss originally (late 14c.) was “to miss the meaning of” (see mistake). Now it means “to misinterpret in a bad sense.”
see under take the wrong way