to kill suddenly or secretively, especially a politically prominent person; murder premeditatedly and treacherously.
to destroy or harm treacherously and viciously:
to assassinate a person’s character.
Historical Examples

Gin you met this ganglin’ assassinator, wha’d be for maister?
The Best Short Stories of 1917 Various

I think that the firing that was done could have been done with the type gun that they say the assassinator used.
Warren Commission (6 of 26): Hearings Vol. VI (of 15) The President’s Commission on the Assassination of President Kennedy

verb (transitive)
to murder (a person, esp a public or political figure), usually by a surprise attack
to ruin or harm (a person’s reputation, etc) by slander

1610s, from past participle stem of Medieval Latin assassinare (see assassin). Of reputations, characters, etc., from 1620s. Related: Assassinated; assassinating.

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