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a female dog:
The bitch won first place in the sporting dogs category.
a female of canines generally.
Slang.

a malicious, unpleasant, selfish person, especially a woman.
a lewd woman.
Disparaging and Offensive. any woman.

Slang. a person who is submissive or subservient to someone, usually in a humiliating way:
Tom is so her bitch—he never questions what she decides.
Slang.

a man who willingly or unwillingly submits to the will and control of a dominant partner in a sexual relationship, especially with another man, as in prison bitch:
Watch out, or your cellmate will make you his prison bitch.
a gay man who assumes the passive or female role in a sexual relationship.

Slang.

a complaint.
See also bitch session.
anything difficult or unpleasant:
That test was a real bitch.
anything memorable, especially something exceptionally good:
You threw one bitch of a party last night.

Slang. to complain; gripe:
They bitched about the service, then about the bill.
Slang. to spoil; bungle (sometimes followed by up):
He bitched the job completely. You really bitched up this math problem.
sit / ride bitch, to sit uncomfortably between two others in the middle of the front or back seat of a car, particularly one with a raised section in the middle resulting in being forced to bring one’s knees up in a bent position:
When I was young, I was the smallest, so I was always stuck sitting bitch. Please don’t make me ride bitch again!
Contemporary Examples

What Should Bachmann’s Theme Song Be? Jimmy So June 28, 2011
Uh, Qualified? Elizabeth Wurtzel December 13, 2008
Pistorius Tries to Dodge Incriminating Details Kelly Berold April 9, 2014
New York’s Sikhs Need Their Own Al Sharpton Dean Obeidallah August 7, 2014
Candidate Caroline Is Off to a Bad Start Elizabeth Wurtzel December 21, 2008
Madonna Caves in French Swastika Kerfuffle Tracy McNicoll August 21, 2012
Chicago’s Gun-Toting Gang Girl: ‘Lil Snoop’ Michael Daly April 28, 2014
Speed Read: 25 Extraordinary Roger Ailes Revelations From ‘The Loudest Voice in the Room’ Lloyd Grove January 13, 2014

Historical Examples

A New Voyage to Carolina John Lawson
The American Language Henry L. Mencken

noun
a female dog or other female canine animal, such as a wolf
(offensive, slang) a malicious, spiteful, or coarse woman
(slang) a complaint
(slang) a difficult situation or problem
(slang) a person who acts as a subordinate or slave to another person
verb (informal)
(intransitive) to complain; grumble
to behave (towards) in a spiteful or malicious manner
(transitive) often foll by up. to botch; bungle
n.

BITCH. A she dog, or doggess; the most offensive appellation that can be given to an English woman, even more provoking than that of whore. [“Dictionary of the Vulgar Tongue,” 1811]

Bitch goddess coined 1906 by William James; the original one was success.
v.

A woman one dislikes or disapproves of, esp a malicious, devious, or heartless woman •The equivalent of the masculine bastard as a general term of opprobrium: a cold-hearted bitch (1400+)
A girl: Some boys commonly use the word ”bitch” as a synonym for ”girl” (1990s+ Black teenagers)
A waspish or insolent male homosexual (1930s+ Homosexuals)
The queen of any suit in playing cards (1900+)
: What’s your bitch today? (1910+)
Anything arduous or very disagreeable: That wind’s a bitch (1814+)
(also biatch, beotch) A person who performs tasks for another and is usually treated in a degrading manner: I’d like you to be my bitch today
Buddy; cohort

(also bitch and moan) To complain; gripe; beef, bellyache: College students always bitch about the food (1930+)
To cheat; chisel: You never tried to bitch me out of anything (1920s+)
(also bitch up) To ruin; mess up (1820s+)