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either of two genes (BRCA1 or BRCA2) that, if inherited in a mutated form, may predispose some carriers to develop breast or ovarian cancer.
Contemporary Examples

It’s in the Genes Megan McArdle June 12, 2013

One of two genes (designated BRCA1 and BRCA2) that help repair damage to DNA, but when inherited in a defective state increase the risk of breast and ovarian cancer.
breast cancer 1 (gene)
Brotherhood of Railway Carmen of America


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