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Chemistry. a usually irreversible chemical reaction involving the rearrangement of the atoms of one or more substances and a change in their chemical properties or composition, resulting in the formation of at least one new substance:
The formation of rust on iron is a chemical change.

any change from one state (gas, liquid, solid) which is accompanied by alteration of the chemical composition; any process in which one or more substances are changed into one or more different substances; cf. physical change

See physical change


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