a syphilitic brain disorder characterized by chronic inflammation and degeneration of cerebral tissue resulting in mental and physical deterioration.
- General paralysis of the insane
noun 1. a disease of the central nervous system: a late manifestation of syphilis, often occurring up to 15 years after the original infection, characterized by mental deterioration, speech defects, and progressive paralysis GPI Also called general paresis, dementia paralytica
noun 1. a partner with unlimited liability for the debts of the partnership.
noun 1. former name of . Abbreviation: GPU.
noun 1. (in the U.S. postal system) the main post office of a city, county, etc., that also has branch post offices. Abbreviation: G.P.O., GPO. noun 1. (in Britain until 1969) the department of the central Government that provided postal and telephone services 2. the main post office in a locality