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Metachromatic leukodystrophy

metachromatic leukodystrophy n.
An inherited metabolic disorder characterized by myelin loss, accumulation of metachromatic lipids in the white matter of the central and peripheral nervous systems, a marked excess of sulfatidates in white matter and in urine, progressive paralysis, and dementia.


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  • Metachromatic stain

    metachromatic stain n. A stain that has the ability to produce different colors in various histological or cytological structures.

  • Metachromatism

    [met-uh-kroh-muh-tiz-uh m] /ˌmɛt əˈkroʊ məˌtɪz əm/ noun 1. change of color, especially that due to variation in the temperature of a body. /ˌmɛtəˈkrəʊməˌtɪzəm/ noun 1. a change in colour, esp when caused by a change in temperature metachromatism met·a·chro·ma·tism (mět’ə-krō’mə-tĭz’əm) n. Metachromasia.

  • Metachromophil

    metachromophil met·a·chro·mo·phil (mět’ə-krō’mə-fĭl’) or met·a·chro·mo·phile (-fīl’) adj. Metachromatic.

  • Metachronous

    [muh-tak-ruh-nuh s] /məˈtæk rə nəs/ adjective 1. Medicine/Medical. occurring at a different time than a similar event: metachronous tumors. 2. Geology. composed of parts formed at different times: The older late-glacial shorelines are metachronous.

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