Mrs.

[mis-iz, miz-iz] /ˈmɪs ɪz, ˈmɪz ɪz/

plural Mmes.
[mey-dahm, -dam] /meɪˈdɑm, -ˈdæm/ (Show IPA)
1.
a title of respect prefixed to the name of a married woman:
Mrs. Jones.
2.
a title prefixed to a mock surname that is used to represent possession of a particular attribute, identity, etc., especially in an idealized or excessive way:
Mrs. Punctuality.

1580s, abbreviation of mistress (q.v.), originally in all uses of that word. The plural Mmes. is an abbreviation of French mesdames, plural of madame, used in English to serve as the plural of Mrs., which is lacking. Pronunciation “missis” was considered vulgar at least into 18c. (cf missus). The Mrs. “one’s wife” is from 1920.
Used as a courtesy title for a married or widowed woman (from “mistress”)