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a combining form meaning “mind,” “diaphragm,” used in the formation of compound words:
combining form
mind or brain: phrenology
of or relating to the diaphragm: phrenic

before vowels phren-, word-forming element meaning “mind,” also “diaphragm,” from Greek phreno-, comb. form of phrene properly “diaphragm, muscle which parts the abdomen from the thorax;” in Homer extended to “parts around the heart, breast,” hence “heart” (as a seat of passions), “mind, seat of thoughts, wits, senses,” of unknown origin.

phreno- or phren- or phreni-


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  • Phrenocardia

    phrenocardia phren·o·car·di·a (frěn’ə-kär’dē-ə) n. Precordial pain and dyspnea of psychogenic origin.

  • Phrenocolic

    phrenocolic phren·o·col·ic (frěn’ō-kŏl’ĭk, -kō’lĭk) adj. Relating to the diaphragm and the colon.

  • Phrenocolopexy

    phrenocolopexy phren·o·col·o·pex·y (frěn’ō-kŏl’ə-pěk’sē, -kō’lə-) n. Suture of a prolapsed transverse colon to the diaphragm.

  • Phrenogastric

    phrenogastric phren·o·gas·tric (frěn’ō-gās’trĭk) adj. Relating to the diaphragm and stomach.

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