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[pahy-ruh-juh n, -jen] /ˈpaɪ rə dʒən, -ˌdʒɛn/

a substance, as a thermostable bacterial toxin, that produces a rise in temperature in a human or animal.
any of a group of substances that cause a rise in temperature in an animal body

1858, as a proposed word for “electricity,” from pyro- + -gen. Meaning “fever-producer” is from 1896. Related: Pyrogenic; pyrogenetic. Greek pyrogenes meant “born in fire, wrought by fire.”

pyrogen py·ro·gen (pī’rə-jən)
A substance that produces a fever.
A polypeptide that produces fever by causing metabolic changes in the hypothalamus. Pyrogens are either exogenous (produced by infectious agents) or endogenous (produced by cells in the body such as macrophages).


Read Also:

  • Pyrogenic

    [pahy-ruh-jen-ik] /ˌpaɪ rəˈdʒɛn ɪk/ adjective 1. producing or produced by heat or fever. 2. Also, pyrogenetic [pahy-roh-juh-net-ik] /ˌpaɪ roʊ dʒəˈnɛt ɪk/ (Show IPA). Geology. produced by heat, as the anhydrous minerals of an igneous rock. /ˌpaɪrəʊˈdʒɛnɪk/ adjective 1. produced by or producing heat 2. (pathol) causing or resulting from fever 3. (geology) less common words […]

  • Pyrogenous

    [pahy-roj-uh-nuh s] /paɪˈrɒdʒ ə nəs/ adjective, Geology. 1. (def 2).

  • Pyroglobulin

    pyroglobulin py·ro·glob·u·lin (pī’rō-glŏb’yə-lĭn) n. Any of various immunoglobulins that coagulate when heated, usually associated with multiple myeloma or macroglobulinemia.

  • Pyrognostics

    [pahy-ruh g-nos-tiks] /ˌpaɪ rəgˈnɒs tɪks/ plural noun 1. those properties of a mineral that it exhibits when heated, alone or with fluxes, in the blowpipe flame, as the fusibility, intumescence, or other phenomena of fusion, flame coloration, etc. /ˌpaɪrɒɡˈnɒstɪks/ plural noun 1. the characteristics of a mineral, such as fusibility and flame coloration, that are […]

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