an abnormal red blood cell having an elongated, crescentlike shape due to the presence of an abnormal hemoglobin.
sickle cell sick·le cell (sĭk’əl)
An abnormal, crescent-shaped red blood cell that results from a single change in the amino acid sequence of the cell’s hemoglobin, which causes the cell to contort, especially under low-oxygen conditions. Also called drepanocyte, meniscocyte.
- Sickle-cell anaemia
noun 1. a hereditary haemolytic anaemia, occurring in Black populations, and caused by mutant haemoglobin. The red blood cells become sickle-shaped. It is characterized by fever, abdominal pain, jaundice, leg ulcers, etc
noun, Pathology. 1. a chronic hereditary blood disease, occurring primarily among Africans or persons of African descent, in which abnormal hemoglobin causes red blood cells to become sickle-shaped and nonfunctional, characterized by enlarged spleen, chronic anemia, lethargy, weakness, joint pain, and blood clot formation. sickle cell anemia n. A chronic, usually fatal inherited form of […]
- Sickle cell c disease
sickle cell C disease n. A hereditary blood disease caused by sickle-shaped red blood cells that contain hemoglobin S and hemoglobin C, characterized by anemia, blocked blood vessels, chronic leg ulcers, and bone deformities.
- Sickle cell disease
sickle cell disease n. See sickle cell anemia.