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[suh-mat-uh-stat-n, soh-muh-tuh-] /səˌmæt əˈstæt n, ˌsoʊ mə tə-/
noun, Biochemistry.
a polypeptide hormone, produced in the brain and pancreas, that inhibits secretion of somatotropin from the hypothalamus and inhibits insulin production by the pancreas.
a peptide hormone that prevents the release of growth hormone from the pituitary gland

somatostatin so·mat·o·stat·in (sō-māt’ə-stāt’n, sō’mə-tə-)
A tetradecapeptide capable of inhibiting the release of somatotropin by the pituitary gland. Also called somatotropin release-inhibiting factor.
(sō-māt’ə-stāt’n, sō’mə-tə-)
A polypeptide produced by the hypothalamus and the pancreas. Somatostatin produced by the hypothalamus acts as a neurohormone that inhibits the secretion of other hormones, especially growth hormone and thyrotropin. Somatostatin secreted by the pancreas acts as a hormone that inhibits the secretion of the other pancreatic hormones, insulin and glucagon, and reduces the activity of the digestive system.


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