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sphingolipidosis sphin·go·lip·i·do·sis (sfĭng’gō-lĭp’ĭ-dō’sĭs)
Any of various diseases, such as gangliosidosis or Gaucher’s disease, characterized by abnormal sphingolipid metabolism. Also called sphingolipodystrophy.


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    [sfing-goh-mahy-uh-lin] /ˌsfɪŋ goʊˈmaɪ ə lɪn/ noun, Biochemistry. 1. any of the class of phospholipids occurring chiefly in the brain and spinal cord, composed of phosphoric acid, choline, sphingosine, and a fatty acid. sphingomyelin /ˌsfɪŋɡəʊˈmaɪəlɪn/ noun 1. (biochem) any of a group of phospholipids, derived from sphingosine, that occur in biological membranes, being especially abundant in […]

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    sphingomyelin lipidosis n. See Niemann-Pick disease.

  • Sphingomyelin phosphodiesterase

    sphingomyelin phosphodiesterase n. An enzyme that catalyzes the hydrolysis of sphingomyelin to ceramide and phosphocholine.

  • Sphingosine

    noun, Biochemistry. 1. a basic unsaturated amino alcohol, C 1 8 H 3 3 (OH) 2 NH 2 , produced by the hydrolysis of sphingomyelin or gangliosides. noun 1. (biochem) a long-chain compound occurring in sphingomyelins and cerebrosides, and from which it can be released by hydrolysis. Formula: CH3(CH2)12CH:CHCH(OH)CH(NH2)CH2OH sphingosine sphin·go·sine (sfĭng’gə-sēn’) n. A basic, […]

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