Variable-region
noun, Immunology.
1.
a configuration in the upper branches of the Y of an antibody molecule, unique in each antibody type, that binds with the determinant of a specific antigen.
variable region
The portion of the amino (NH2) terminal of an antibody’s heavy and light chains having a variable amino acid sequence. The structure of the variable region determines the antigenic specificity of the antibody. Compare constant region.
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[wah-ri-ah lek-ti-oh; English vair-ee-uh lek-shee-oh] /ˈwɑ rɪˌɑ ˈlɛk tɪˌoʊ; English ˈvɛər i ə ˈlɛk ʃiˌoʊ/ noun, plural variae lectiones [wah-ri-ahy lek-ti-oh-nes; English vair-ee-ee lek-shee-oh-neez] /ˈwɑ rɪˌaɪ ˌlɛk tɪˈoʊ nɛs; English ˈvɛər iˌi ˌlɛk ʃiˈoʊ niz/ (Show IPA). Latin. 1. a variant reading.