Amyotrophic lateral sclerosis 1
ALS1. A form of amyotrophic lateral sclerosis (ALS) inherited in an autosomal dominant manner and caused by mutation in the superoxide dismutase-1 gene (SOD1) on chromosome 21q22.1. About 15 to 20% of familial ALS is type 1 (ALS1). Sporadic cases of ALS are sometimes due to new mutation in the SOD1 gene.
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- Amyotrophic lateral sclerosis 2
ALS2. A juvenile-onset form of amyotrophic lateral sclerosis (ALS) inherited in an autosomal recessive manner and caused by mutation in the gene encoding alsin on chromosome 2q33.
- Amyotrophic lateral sclerosis 3
ALS3. An adult-onset form of amyotrophic lateral sclerosis (ALS) inherited in an autosomal dominant manner and caused by mutation in a gene on chromosome 18q21.
- Amyotrophic lateral sclerosis 4
ALS4. A juvenile-onset form of amyotrophic lateral sclerosis (ALS) with no bulbar involvement, inherited in an autosomal dominant manner and caused by mutation in a gene on chromosome 9q34.
- Amyotrophic lateral sclerosis 5
ALS5. A form of amyotrophic lateral sclerosis (ALS) inherited in an autosomal recessive manner due to mutation in a gene on chromosome 15q15.1-q21.1.
- Amyotrophic lateral sclerosis 6
ALS6. A form of amyotrophic lateral sclerosis (ALS) inherited in an autosomal dominant manner due to mutation in a gene on chromosome 16q12.