Angiosarcoma: A form of tissue cancer (sarcoma) that arises in the lining of blood vessels. Angiosarcomas tend to be aggressive, recur locally, and spread widely. Predisposing factors include lymphedema (as from a radical mastectomy), radiotherapy, foreign materials (such as steel and plastic) in the body, and environmental agents (such as arsenic solutions used to spray grapevines and vinyl chloride in the plastic industry).
Angiostatin: A fragment of a protein, plasminogen, that is involved in blood clotting. Angiostatin is normally secreted by tumors, and it appears to halt the process of developing new blood vessels, which is necessary to tumor development.
Angiostrongyliasis: Infection with the parasitic nematode (roundworm) Angiostrongylus. The two species that infect humans are A. cantonensis and A. costaricensis. A. cantonensis, the rat lungworm, is the most common cause of human eosinophilic meningitis (meningitis with eosinophils in the cerebrospinal fluid). The meningitis is due to the presence of the rat lungworm larvae in the […]
- Angiostrongylus infection
Angiostrongylus infection: Also called angiostrongyliasis. See: Angiostrongyliasis.
Angiotensin: A family of peptides that constrict blood vessels. Narrowing the diameter of the blood vessels causes blood pressure to rise.
- Angiotensin converting enzyme 2
Angiotensin converting enzyme 2: An enzyme, abbreviated ACE2, that is an essential regulator of heart function. It may also be involved in the embryonic development of the heart. ACE2 was discovered in 2000. The gene for it has been mapped to the X chromosome (band Xp22).