Antibody cross reactivity


Antibody cross reactivity: The ability of an antibody to react with similar antigenic sites on different proteins.

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  • Antibody, antinuclear

    Antibody, antinuclear: An unusual antibody that is directed against structures within the nucleus of the cell. Antinuclear antibodies (ANAs) are found in patients whose immune system is predisposed to cause inflammation against their own body tissues. Antibodies that are directed against one’s own tissues are referred to as autoantibodies. The propensity for the immune system […]

  • Antibody, antithyroglobulin

    Antibody, antithyroglobulin: An antibody directed against thyroglobulin which is a key protein in the thyroid gland essential to the production of thyroid hormones (thyroxine and triiodothyronine). Antithyroglobulin antibodies can damage the thyroid gland and affect its function. Testing for antithyroglobulin antibodies in the blood is useful in the diagnosis of some thyroid and other disorders. […]

  • Antibody-dependent cell-mediated cytotoxicity

    Antibody-dependent cell-mediated cytotoxicity: An immune response in which antibody, by coating target cells, makes them vulnerable to attack by immune cells. Antibody-dependent cell-mediated cytotoxicity is commonly abbreviated ADCC.

  • Anticholinergic

    Anticholinergic: Opposing the actions of the neurotransmitter acetylcholine. Anticholinergic drugs inhibit the transmission of parasympathetic nerve impulses, thereby reducing spasms of smooth muscles (for example, muscles in the bladder). Side effects of anticholinergic medications include dry mouth and related dental problems, blurred vision, tendency toward overheating (hyperpyrexia), and in some cases, dementia-like symptoms.

  • Anticipation

    Anticipation: The progressively earlier appearance and increased severity of a disease from generation to generation. The phenomenon of anticipation was once thought to be an artifact, but a biological basis for it has been discovered in a number of genetic disorders, such as myotonic dystrophy and Huntington disease.


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