Antisense DNA: DNA normally has two strands, i.e., the sense strand and the antisense strand. In double-stranded DNA, only one strand codes for the RNA that is translated into protein. This DNA strand is referred to as the antisense strand. The strand that does not code for RNA is called the sense strand. Another way of defining antisense DNA is that it is the strand of DNA that carries the information necessary to make proteins by binding to a corresponding messenger RNA. Although these strands are exact mirror images of one another, only the antisense strand contains the information for making proteins. The sense strand does not.
Antisense DNA is also known as noncoding DNA.
- Antisense drug
Antisense drug: A medication containing part of the non-coding strand of messenger RNA (mRNA), a key molecule involved in the translation of DNA into protein. Antisense drugs hybridize with and inactivate mRNA. This stops a particular gene from producing the protein for which it holds the recipe. Antisense drugs have been developed or are “in […]
- Antisense mRNA
Antisense mRNA: An mRNA (messenger RNA) transcript that is complementary to endogenous mRNA. Antisense mRNA is the noncoding strand complementary to the coding sequence of mRNA. Introducing a transgene coding for antisense mRNA is a strategy used to block expression of a gene of interest.
Antisepsis: Prevention of infection by inhibiting or arresting the growth and multiplication of germs (infectious agents). Antisepsis implies scrupulously clean and free of all living microorganisms. From the Greek roots anti- meaning against + sepsis against putrefaction = literally, against putrefaction.
Antiseptic: Something that discourages the growth microorganisms. By contrast, aseptic refers to the absence of microorganisms.
- Antisocial personality disorder
frequent imprisonment for unlawful behavior, alcoholism and drug abuse. Samson may, it is thought, have had antisocial personality disorder. The Bible tells of his lies to his parents, his cruelty to animals, his torching the Philistine fields, his frequent brawls, and his unremitting bragging after killing a thousand men, actions fitting the diagnosis of antisocial […]