APC (immunology): Antigen-presenting cell, a cell that can “present” antigen in a form that T cells can recognize it. Among the APCs are B cells and cells of the monocyte lineage including macrophages.
- APC (medication)
APC (medication): Aspirin, phenacetin, and caffeine (a pill containing all three). Phenacetin was the first nonsteroidal anti-inflammatory drug (NSAID) to be associated with kidney failure.
- APECED (autoimmune polyendocrinopathy)
APECED (autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy): A genetic autoimmune disease with an extraordinary array of clinical features but characterized most often by at least 2 of the following 3 findings: hypoparathyroidism — underfunction of the parathyroid glands which control calcium, candidiasis (yeast infection), and adrenal insufficiency (underfunction of the adrenal gland). APECED was the first systemic (bodywide) […]
- Apert syndrome
Apert syndrome: A malformation syndrome characterized by a high short skull, underdevelopment of the midface, soft tissue and bony (“mitten glove”) fusion of fingers and toes, fusion of the neck vertebrae, and varying degrees of developmental delay/mental retardation. The frequency of the syndrome rises with the age of the father reflecting the fact that the […]
- Apert syndrome acrocephalosyndactyly
Apert syndrome acrocephalosyndactyly: An inherited disorder causing abnormalities of the skull, face and hands and feet. There is premature closure of some of the sutures of the skull (craniosynostosis) resulting in an abnormally shaped head (which is unusually tall but short from front-to-back) and an abnormally shaped face (with shallow eye sockets and underdevelopment of […]
Apex: The Latin word for summit, the apex is the tip of a pyramidal or rounded structure, such as the lung or the heart. The apex of the lung is indeed its tip’its rounded most superior portion. The apex of the heart is likewise its tip, but it is formed by the left ventricle, so […]